Procedure demonstrates the efficient synthesis of indanones from cyclopropanols, suggesting new applications in drug development.
Herein, we report a nickel-catalyzed intramolecular arylation of cyclopropanols. This protocol enables the synthesis of a broad scope of substituted indanones from readily available starting materials. This approach could be applied to the synthesis of the drug Donepezil.
No takes yet. Share an insight, caveat, or question.
Liang et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: