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September 10, 2025The Journal of Agricultural Science

Copy number variation profiling in the genome of crossbred dairy cattle from Pakistan

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Authors

FNFakhar un NisaMAMuhammad AsifQNQamar Un Nisa

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Overview

This analysis identifies copy number variations and their associations with traits in crossbred dairy cattle, suggesting potential for improved milk production.

Key Points

  • The study identified 1055 copy number variations in the genomes of crossbred dairy cattle, improving trait mapping.
  • Using a GGP_HDv3_C chip with 139,376 SNPs, researchers detected 268 significant CNVRs covering 31.03 megabases of the bovine genome.
  • Functional analysis revealed 97 genes linked to immune response, health, and production traits within the identified CNVRs.
  • Findings support targeted selection strategies for enhancing milk yield and adaptability in tropical environments.

Cite This Study

Nisa et al. (2025) studied this question.

synapsesocial.com/papers/68c1a25a54b1d3bfb60dd3a6https://doi.org/10.1017/s0021859625100208
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Genome-wide copy number variation regions in indigenous (Bos indicus) cattle breeds of Tamil Nadu, India2024 · 4 citations
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  3. 3Genome-wide association analyses reveals copy number variant regions associated with reproduction and disease traits in Canadian Holstein cattle2024 · 13 citations
  4. 4Detection and evaluation of copy number variation using both linked-read and short-read sequencing in New Zealand dairy cattle2026
  5. 5121 Copy number variation: From mapping to variance components in Holsteins2024