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September 10, 2025American Journal of Translational Research

Comparison of the analgesic efficacy of ultrasound-guided retrolaminar block with serratus anterior plane block in patients undergoing radical mastectomy

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Authors

ZDZewu DingXWXihui WangDHDongdong Han

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Overview

Randomized trial compares analgesic effectiveness of retrolaminar and serratus anterior plane blocks in radical mastectomy patients, suggesting comparable outcomes.

Key Points

  • Both retrolaminar block and serratus anterior plane block provide comparable analgesia after radical mastectomy, with median VAS scores of 2 for both techniques.
  • The study included 70 patients and found RLB offered significantly broader sensory coverage on the medial side of the nipple compared to SAPB, with a median score of 3 vs 2.
  • Intraoperative hemodynamic changes, mean arterial pressure, and heart rate showed no significant differences between the two groups during surgery.
  • The incidence of adverse events was similar across both analgesic techniques, highlighting their safety in postoperative care for mastectomy patients.

Cite This Study

Ding et al. (2025) studied this question.

synapsesocial.com/papers/68c1a26154b1d3bfb60dd4f7https://doi.org/10.62347/pucp3777
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Paravertebral block: cervical, thoracic, lumbar, and sacral2009 · 76 citations
  2. 2The analgesic efficacy of a single injection of ultrasound-guided retrolaminar paravertebral block for breast surgery: a prospective, randomized, double-blinded study2020 · 16 citations
  3. 3An anatomical evaluation of the serratus anterior plane block2016 · 281 citations