Study demonstrates IVIG lots contain neutralizing antibodies against resistant Omicron variants, indicating potential protection.
Our study demonstrates that IVIG lots manufactured in 2023–2024 contain neutralizing antibodies against circulating Omicron variants, including KP.3 and XEC. These variants are resistant to all convalescent plasma and IVIG preparations produced prior to 2023. Therefore, recent IVIG lots may provide some protection against COVID-19 caused by circulating SARS-CoV-2 variants.
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Liu et al. (2025) studied this question.
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