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September 10, 2025European Heart Journal Supplements

Progression of pulmonary arterial systolic pressure after chemotherapy is a poor prognostic factor in patients with multiple myeloma

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Authors

HYHyun Ju YoonChonnam National University HospitalHPH J ParkNLNelson LeeUniversity of Toronto

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Implication

Observational analysis finds progression of pulmonary arterial systolic pressure predicts poor prognosis in multiple myeloma, highlighting the need for regular check-ups.

Key Points

  • Progression of pulmonary arterial systolic pressure is linked to a significantly higher mortality rate in patients with multiple myeloma during follow-up.
  • In total, 62 patients had pulmonary hypertension at baseline, with 15.8% showing de novo pulmonary hypertension post-chemotherapy.
  • Kaplan Meier survival analysis revealed that the progression of pulmonary arterial systolic pressure leads to significantly lower survival rates.
  • Regular monitoring of pulmonary arterial systolic pressure via echocardiography is crucial for identifying high-risk multiple myeloma patients.

Cite This Study

Yoon et al. (2025) studied this question.

synapsesocial.com/papers/68c1a5e554b1d3bfb60df239https://doi.org/10.1093/eurheartjsupp/suaf083.095
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of elevated pulmonary artery systolic pressure with hematologic progression in myeloproliferative neoplasms.2024 · 1 citations
  2. 2Elevated Pulmonary Artery Systolic Pressure is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer2020 · 14 citations
  3. 3Long-term follow-up in outpatients with mildly elevated pulmonary artery systolic pressure on echocardiography: a single-centre retrospective cohort study in Shanghai, China2024 · 1 citations
  4. 4Impact of pulmonary hypertension on in-hospital outcomes among patients hospitalized with multiple myeloma: A 2015–2022 national inpatient sample analysis2025
  5. 5Long term survival of patients with raised pulmonary arterial systolic pressure utilizing echocardiography—a five-year prospective study2013 · 1 citations