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Recent Advances in the Multifunctionalization Reactions of Indoles

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This review highlights developments in multifunctionalization reactions of indoles, emphasizing catalytic systems and regioselectivity.

Multifunctionalization reactions of indoles have been enhanced, driving innovations in drug discovery.
Key methodologies include cyclization, di‐ and trifunctionalization, with varied catalytic systems showcased.
Regioselectivity control and compatibility of functional groups are vital for effective indole reactions.
The review serves as a reference for future advancements in indole chemistry, fostering breakthroughs.

Zhang et al. (2025) studied this question.

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