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September 10, 2025Urology HeraldOpen Access

Molecular genetic subtypes of non-muscle-invasive bladder cancer: their impact on disease prognosis

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Retrospective analysis reveals recurrence and progression risks across molecular genetic subtypes in NMIBC, suggesting tailored treatment approaches.

Basal-squamous-like tumors demonstrate the worst prognosis, necessitating more aggressive treatment.
Luminal tumors show low recurrence at 33.3% and progression at 2.1%, indicating favorable outcomes.
Tumors categorized by molecular subtypes exhibited significant differences in recurrence and progression rates.
A retrospective study of 162 NMIBC patients revealed distinct patterns in prognosis based on tumor subtypes.

Sargsian et al. (2025) studied this question.

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Retrospective analysis reveals recurrence and progression risks across molecular genetic subtypes in NMIBC, suggesting tailored treatment approaches.