19F NMR as a Tool to Probe Drug Binding and Structural Dynamics in Ferritin-Based Nanocarriers

Veronica Ghini; Giorgio Di Paco; Lucrezia Cosottini; Antonio Rosato; Paola Turano

doi:10.1039/d5ma00538h

January 1, 2025Materials AdvancesOpen Access

19F NMR as a Tool to Probe Drug Binding and Structural Dynamics in Ferritin-Based Nanocarriers

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Key Points

The research demonstrated that ferritin-based nanocarriers effectively bind drugs, enhancing their delivery capabilities.
Key evidence showed improved binding interactions in nanocarriers, suggesting a reliable platform for targeted therapies.
Analysis utilized 19F NMR to assess drug interactions and structural dynamics, providing critical insights into nanocarrier behavior.
Findings imply that ferritin-based systems may revolutionize drug delivery, highlighting their potential in therapeutic applications.

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Implication

Observational analysis examined drug binding and structural dynamics in ferritin nanocarriers, indicating potential for targeted drug delivery.

Abstract

Ferritin-based nanocarriers offer a promising platform for targeted drug delivery due to their biocompatibility, stability, and ability to cross biological barriers. In this study, we used human heavy chain ferritin...

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Ghini et al. (2025) studied this question.

synapsesocial.com/papers/68c1a77254b1d3bfb60e07ce https://doi.org/10.1039/d5ma00538h

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19F NMR as a Tool to Probe Drug Binding and Structural Dynamics in Ferritin-Based Nanocarriers

Key Points

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Abstract

Discussion

Cite This Study

19F NMR as a Tool to Probe Drug Binding and Structural Dynamics in Ferritin-Based Nanocarriers

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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