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September 10, 2025Cancer Management and ResearchOpen Access

Hypopharyngeal Squamous Cell Carcinoma in Elderly Patients Aged ≥70 Years: Surgery and Postoperative Radiotherapy Improves Outcomes in Selected Patients

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Authors

RWRu WangAHAhmad HaririHTHengmin Tao

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Overview

Retrospective analysis shows improved overall survival and disease-free survival in elderly patients, suggesting surgery combined with radiotherapy is effective.

Key Points

  • At one year, patients receiving surgery plus radiotherapy had significantly higher overall survival rates compared to surgery alone.
  • Three-year overall survival rates were 77.3% for surgery plus radiotherapy versus 61.5% for surgery only, indicating a meaningful benefit.
  • N staging and treatment modality emerged as key independent predictors of overall survival and disease-free survival in elderly patients.
  • The study achieved complete follow-up with a median duration of 62 months, showing good tolerance to the treatment in this age group.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c1a77254b1d3bfb60e083chttps://doi.org/10.2147/cmar.s529332
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