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September 10, 2025Current Opinion in Allergy and Clinical Immunology

Where eye meets body part 1: uniting allergy pathways in ocular and nasal disease – IgE on the offense

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Authors

SBSebastian BorgesVPVânia PereiraCCChristopher Chang

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Overview

This review highlights the shared immunologic pathways in allergic rhinitis and conjunctivitis, suggesting a complex relationship between SAR and SAC.

Key Points

  • Up to 71% of patients with SAR report conjunctival symptoms, revealing significant overlap between ocular and nasal allergies.
  • Shared mechanisms include IgE-mediated processes and mast cell activation, underlining the need for integrated treatment approaches.
  • Combination treatments, like intranasal corticosteroids with antihistamines, enhance control in patients with PAR, exemplifying personalized care.
  • Novel drug delivery systems show potential in managing PAC, highlighting the importance of ongoing research in allergy therapies.

Cite This Study

Borges et al. (2025) studied this question.

synapsesocial.com/papers/68c1a77a54b1d3bfb60e0c91https://doi.org/10.1097/aci.0000000000001096
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