Fluorescent probe tracks NAD(P)H and mitochondrial function in dopaminergic toxicity models, indicating metabolic disruptions.
A novel dual-functional fluorescent probe was developed enabling real-time tracking of intracellular NAD(P)H flux and mitochondrial functional decline at the single-cell level with high precision. This probe could assess mitochondrial damage and energy metabolism disruptions in PD-related dopaminergic toxicity models.
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Tang et al. (2025) studied this question.
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