Kasabach-Merritt Syndrome in Neonates: A Case of Complexity and Care

Kasabach-Merritt syndrome (KMS) is a rare and potentially life-threatening pediatric coagulopathy characterized by thrombocytopenia, microangiopathic hemolytic anemia, and coagulation abnormalities. Clinically, it presents as a reddish-purple mass resembling a hemangioma. Diagnosis relies on a combination of clinical and biological assessments, sometimes supplemented by biopsy to confirm the hemangioma. We present the case of a one-day-old male neonate with an angioma affecting the right hemothorax and upper limb, accompanied by thrombocytopenia. The patient responded favorably to treatment with corticosteroids, chemotherapy, and aspirin. Therapeutic strategies were carefully evaluated and discussed.