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The value of prenatal indicators in predicting adverse fetal outcomes in patients with ICP

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Observational case-control study highlights prenatal markers predicting adverse fetal outcomes in cholestasis of pregnancy.

Prenatal laboratory indicators significantly predict adverse fetal outcomes in patients with cholestasis of pregnancy.
Total bile acids and cholyglycine were notably higher in ICP cases with adverse outcomes, indicating a potential risk.
Multivariate analysis revealed that cholyglycine and fibrinogen levels are independently associated with adverse fetal outcomes.
This study suggests the importance of monitoring specific biomarker levels in pregnancies affected by cholestasis.

Jiang et al. (2025) studied this question.

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