Monitoring, surveillance, antimicrobial resistance and genetic diversity analysis of non-typhoidal Salmonella in South Africa from 1960–2023 from animal and animal products
Retrospective analysis shows significant shifts in non-typhoidal salmonella serotypes and rising antimicrobial resistance, emphasizing the need for improved surveillance.
Key Points
A significant rise in antimicrobial resistance in non-typhoidal salmonella was observed, particularly for cefoxitin and tetracycline.
The study analyzed 1,028 salmonella isolates over 63 years, revealing notable shifts in serotype dynamics.
Genetic analysis identified S. Gallinarium with over 70% prevalence of antibiotic resistance genes, indicating a concerning trend.
These findings underscore the urgency of implementing effective antimicrobial stewardship and surveillance strategies.