Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Drug Design Development and TherapyOpen Access

Effect of Perioperative Subanesthetic Dose of Esketamine on Postoperative Recovery Quality in Patients Undergoing Laparoscopic Gastrointestinal Surgery: A Randomised, Double-Blind, Controlled Trial

View Full Paper
Ask AI
Bookmark
Share

Authors

YZYe ZhangSLShuqin LiCWCheng Wu

Discussion

Loading...

Member takes

Overview

Randomised trial shows improved recovery quality and lower pain scores in patients undergoing laparoscopic surgery, indicating benefits of esketamine anesthesia.

Key Points

  • Esketamine significantly improved postoperative recovery quality compared to the control group.
  • Patients receiving esketamine reported higher QoR-40 scores at 1, 3, and 5 days after surgery.
  • Lower resting NRS pain scores were observed in the esketamine group at multiple postoperative time points.
  • This trial suggests perioperative esketamine may enhance recovery and reduce pain in laparoscopic surgery patients.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68c1a91354b1d3bfb60e27c9https://doi.org/10.2147/dddt.s502718
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of esketamine on serum neurotransmitters in patients with postpartum depression: a randomized controlled trial2024 · 13 citations
  2. 2Effect of subanesthetic dose of esketamine on postoperative pain in elderly patients undergoing laparoscopic gastrointestinal tumor Surgery:A prospective, double-blind, randomized controlled trial2024 · 22 citations
  3. 3Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala2018 · 16 citations
  4. 4Pharmacokinetics and Safety of Esketamine in Chinese Patients Undergoing Painless Gastroscopy in Comparison with Ketamine: A Randomized, Open-Label Clinical Study2019 · 216 citations
  5. 5Efficacy of Intravenous Administration of Esketamine in Preventing and Treating Rebound Pain After Thoracic Paravertebral Nerve Block: A Prospective Randomized, Double-Blind, Placebo-Controlled Trial2024 · 27 citations