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September 10, 2025Food Science & Nutrition0 citationsOpen Access

Antidiabetic Potential and Phytochemical Profiling of Atriplex Halimus Extracts

Phytochemical Profiling, Antioxidant Capacity, and the Antidiabetic Potential of Atriplex halimus Extracts: UHPLC–MS/MS Analysis, In Vitro Enzyme Inhibition Assays, and Molecular Docking Studies

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Authors

MRMohammed RoubiNDNour Elhouda DaoudiMDMohammed Dalli

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Overview

In vitro enzyme inhibition shows Atriplex halimus extracts have significant antidiabetic properties, indicating strong antioxidant activity.

Key Points

  • Atriplex halimus extracts significantly inhibit α-amylase and hemoglobin glycation, suggesting potent antidiabetic effects.
  • UHPLC-MS/MS analysis identified 21 phytochemicals with trans-cinnamic acid being the most abundant compound across extracts.
  • Molecular docking reveals catechin and epigallocatechin as active compounds with stronger binding than acarbose.
  • These findings support the use of Atriplex halimus extracts as natural therapeutic agents in diabetes management.

Cite This Study

Roubi et al. (2025) studied this question.

synapsesocial.com/papers/68c1aabf54b1d3bfb60e2d92https://doi.org/10.1002/fsn3.70745
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