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September 27, 2025PLoS ONEOpen Access

Investigation of phytochemical and biochemical attributes of hypoglycemic activity of Atriplex crassifolia (C.A. Mey) extracts in alloxan diabetic animal model

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Authors

SRSarah RehmanSISaiqa IshtiaqSKSairah Hafeez Kamran

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Overview

Assessment finds Atriplex crassifolia extracts lower blood glucose levels in diabetic rats, suggesting their potential therapeutic role.

Key Points

  • Atriplex crassifolia extracts significantly reduced blood glucose levels in an alloxan-induced diabetic model.
  • Key extracts, ACEA and ACNB, demonstrated notable hypoglycemic effects during oral glucose tolerance tests.
  • The study employed various doses to evaluate the extracts' effectiveness over a 28-day treatment period.
  • Histopathological analysis confirmed the safety and effectiveness of Atriplex crassifolia extracts in reducing hyperglycemia.

Cite This Study

Rehman et al. (2025) studied this question.

synapsesocial.com/papers/68d7b3d4eebfec0fc5236587https://doi.org/10.1371/journal.pone.0333425
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