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September 10, 2025KIDNEYSOpen Access

Immune response on interferon-gamma in rats infected with C.albicans

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A significant increase in IFN-γ concentration was observed in Candida albicans-infected rats, indicating changes in immune response.
Analysis showed notable rises in IL-10 levels among infected rats compared to controls, suggesting an active immune modulation.
The temporal and sex-dependent variations in IFN-γ levels underscore the cytokine's critical role in tackling Candida albicans infections.
The absence of significant differences between male and female rats points to the influence of other factors on IFN-γ regulation during infection.

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Observational analysis reveals IFN-γ levels fluctuate in response to Candida albicans infection in rats, suggesting immune system complexities.

Mohammed et al. (2025) studied this question.

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Observational analysis reveals IFN-γ levels fluctuate in response to Candida albicans infection in rats, suggesting immune system complexities.