Case study reveals malignant transformation of leiomyoma in nasal cavity, highlighting treatment options.
Leiomyosarcoma (LMS) is a malignant tumor of smooth muscle origin that is most frequently found in the uterus and gastrointestinal tract. LMS involving the head and neck is rare, accounting for only 2.3% of all cases. In this region, LMS tends to be more aggressive and is associated with a poorer prognosis compared to its gastrointestinal counterparts. Furthermore, LMS of the nasal cavity and paranasal sinuses is extremely rare. Here, we present a case of malignant transformation of a leiomyoma originating from the inferior turbinate, which was successfully treated with endoscopic tumor resection followed by postoperative radiotherapy.
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Park et al. (2025) studied this question.
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