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September 10, 2025Journal of ChemistryOpen Access

Potential of Herbal Essential Oils as Denture Cleansers Against Biofilm Formation on Dental Acrylic Resin: In Vitro and In Silico Approaches

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Authors

NSNurdan Polat SağsözLGLeyla GüvenBGBahri Gür

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Overview

In vitro analysis shows essential oils reduce biofilm of Candida albicans on dental resin, suggesting effective denture cleaners.

Key Points

  • Essential oils effectively reduced biofilm formation on dental resin samples, indicating potential as denture cleansers.
  • The anticandidal effect of Cinnamomum zeylanicum was highest at low concentrations, outperforming chemical denture cleaners.
  • In silico studies revealed significant inhibition of SAP-2 protein, emphasizing the molecular mechanisms behind essential oils' efficacy.
  • Cytotoxicity in NIH/3T3 cells was observed at certain concentrations, highlighting safety considerations for essential oil use.

Cite This Study

Sağsöz et al. (2025) studied this question.

synapsesocial.com/papers/68c1aac654b1d3bfb60e3232https://doi.org/10.1155/joch/4595925
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparative Evaluation of Antifungal Action of Tea Tree Oil, Cinnamon Oil and Fluconazole on Heat Polymerized Acrylic Denture Base Resin - an in Vitro Study2024 · 1 citations
  2. 2Essential Oils from the Perspective of Dentistry2024 · 1 citations
  3. 3Antibiofilm Activity of a Thermoformable Material Loaded With Essential Oil Solution2026
  4. 4Effectiveness of Patchouli Leaf Extract (Pogostemon cablin) with Varying Concentrations as an Acrylic Denture Cleanser against the Growth of Candida albicans: An Experimental Laboratory Study2024
  5. 5Effects of cleaning agents and Candida Biofilms on dental resin integrity2026