Neonatal Septic Arthritis Caused by Escherichia coli: A Case Report from Saudi Arabia

Prompt diagnosis and treatment of neonatal septic arthritis (SA) is crucial to prevent severe complications such as joint deformity and long-term disability. This report details the case of a 16-day-old male neonate presenting with localised swelling, erythema, and restricted movement of the right knee, ultimately diagnosed with Escherichia coli-induced septic arthritis—a previously undocumented finding in Saudi Arabia. The diagnosis was confirmed via synovial fluid culture, and management included the administration of broad-spectrum antibiotics adjusted according to sensitivity, as well as surgical intervention. This case highlights the significance of an early, multidisciplinary approach in managing neonatal septic arthritis and adds to the literature on atypical causative pathogens.