Randomized trials evaluated the effect of iron and folic acid on haemoglobin and ferritin levels in pregnant women, suggesting their crucial role in addressing deficiencies.
In India, there are substantial inter-state and urban-rural variations in the prevalence of anaemia and iron, folic acid and vitamin B 12 deficiency in pregnant women as well as the type and dose of micro-nutrient supplements provided in antenatal clinics. Our institution had conducted two hospital-based randomized studies on treatment of anaemia in pregnant women with Haemoglobin (Hb) between 8.0 to 10.9 g/dL with different doses of iron, folic acid and vitamin (vit) B12. Blood samples were collected at enrolment and after 8 weeks of supplementation and Hb, ferritin, C reactive protein (CRP), folic acid and Vitamin B 12 levels were estimated.
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Prema Ramachandran (2025) studied this question.
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