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September 10, 2025Journal of Clinical MedicineOpen Access

Pars Plana Vitrectomy Combined with Anti-VEGF Injections as an Approach to Treat Proliferative Diabetic Retinopathy

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Authors

RLRafał LeszczyńskiWOWojciech OlszowskiMKMarcin Karcz

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Overview

Observational analysis improved visual acuity in patients with proliferative diabetic retinopathy, indicating benefits of anti-VEGF therapy.

Key Points

  • Preoperative anti-VEGF therapy improved visual acuity significantly, achieving 0.24 logMAR compared to 0.37 in the control group.
  • Intraocular pressure was lower in the study group at 16.84 mmHg, highlighting potential safety in using anti-VEGF.
  • Surgical duration was reduced in the study group with an average of 47.62 minutes, compared to 50.05 minutes in controls.
  • Frequency of surgery-induced retinal breaks was significantly lower at 0.34 in the study group versus 0.56 in controls.

Cite This Study

Leszczyński et al. (2025) studied this question.

synapsesocial.com/papers/68c1aad354b1d3bfb60e3a28https://doi.org/10.3390/jcm14155349
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adjuvant Anti-VEGF in Vitrectomy for Proliferative Diabetic Retinopathy: Current Evidence, Timing Considerations, and Clinical Implications2026
  2. 2Clinical Characteristics of Proliferative Diabetic Retinopathy and Outcome of Pars Plana Vitrectomy in Proliferative Diabetic Retinopathy2024 · 2 citations
  3. 3Comparison of Intravitreal Antivascular Endothelial Growth Factor Therapy in Treatment-Naïve vs Panretinal Photocoagulation–Treated Eyes With Proliferative Diabetic Retinopathy2026 · 1 citations
  4. 4Progression to Pars Plana Vitrectomy in Patients With Proliferative Diabetic Retinopathy2024 · 11 citations
  5. 5New Approaches to Surgical Treatment of Patients with Advanced Stage of Proliferative Diabetic Retinopathy2024 · 1 citations