The use of a computer program in the diagnosis of chronic rhinosinusitis

Purpose of research is to develop a computer program to improve the diagnosis and monitoring of treatment of pa- tients with chronic rhinosinusitis. Methods . The program was developed on the basis of multifactorial and correlation analyses, taking into account a combination of indicators of invasive laboratory diagnostic methods. Laboratory diagnostics is performed for biomarkers of endothelial dysfunction in peripheral blood samples of patients (homocysteine, cystatin C, highly sensitive C-reactive protein (hsCRB), D-dimer). The certificate of state registration of the computer program No. 2021611887 dated 02/08/2021 was received. Results . The program is based on protocols of clinical and laboratory examination of patients with chronic rhinosinusitis. The program operates according to the following stages: data input; mathematical calculation using a mathematical model; output of a digital result of the value "y"; generation of a report with the output of the result on the screen. The program has such qualities as visibility and ease of use. Clinical cases are given as examples of the program's work. The operation of the program is demonstrated in the form of an interface image. Conclusion . The developed software can be recommended for use in clinical practice. In the pre- and postoperative periods, with the help of this program, it is possible to conduct treatment monitoring using objective standardized highly sensitive clinical and laboratory research methods. The implementation of the software package in practice will help to implement an integrated approach in the diagnosis of CRS. The presented program is an innovative tool for the diagnosis and evaluation of the effectiveness of treatment in patients with CRS. The developed program can be recommended for use in the routine practice of an otorhinolaryngologist in outpatient and hospital settings of healthcare institutions.