Inhibition panel assay evaluates SLC transporters affecting drug absorption, indicating possible interactions.
SLC (Solute Carrier) transporters play a crucial role in drug absorption, distribution, and elimination.Some drugs can act as inhibitors of these transporters, potentially affecting the absorption or clearance of other co-administered drugs, leading to drug interactions.This can result in altered drug concentrations and potentially affect efficacy or increase toxicity. Transporters used were OATP1B1, OATP1B3, OAT1, OAT3, OCT2, MATE1, and MATE2-K
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Nick Lynch (2025) studied this question.
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