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September 10, 2025

Oxidative Stress of Cyclosporine on Kidney Functions and Antioxidant Role of Cinnamon

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This study investigates oxidative stress from cyclosporine A and the antioxidant effects of cinnamon extract on kidney functions.

Cyclosporine A treatment significantly reduced sodium and potassium levels in male rabbits, impacting kidney functions.
Treatment with cyclosporine A showed an increased level of TBARS, indicating oxidative damage compared to control.
Cinnamon extract appears to mitigate some negative effects of cyclosporine A, positively influencing antioxidant levels.
The findings highlight the detoxification role of glutathione-S-transferase in kidney health affected by oxidative stress.

A 2025 study studied this question.

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