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September 10, 2025Western Journal of Emergency MedicineOpen Access

Retention Challenges in Opioid Use Disorder Treatment: The Role of Comorbid Psychological Conditions

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Authors

DSDavid C. SeabergJMJamie McKinnonLHLyn Haselton

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Overview

Observational analysis reveals lower retention in opioid use disorder patients with comorbid psychological conditions, indicating a need for targeted interventions.

Key Points

  • Retention rates in the opioid use disorder treatment program were 47% at one month and 25% at six months, highlighting significant challenges.
  • Those with higher income had a stronger correlation (0.51) with six-month retention, suggesting financial stability plays a key role in treatment success.
  • Post-traumatic stress disorder scores from baseline showed significant impact on retention, indicating trauma history complicates treatment adherence.
  • Using validated psychological surveys could assist in predicting retention in opioid use disorder patients, pointing to a potential intervention strategy.

Cite This Study

Seaberg et al. (2025) studied this question.

synapsesocial.com/papers/68c1abf954b1d3bfb60e42abhttps://doi.org/10.5811/westjem.38089
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Emergency Department-Based Medication for Opioid Use Disorder Program: Addressing Gaps in Linkages to Care2024
  2. 2Retention on Buprenorphine for Opioid Use Disorder in Justice-Involved Individuals: A Retrospective Cohort Study2026
  3. 3Digitally-enhanced medication-assisted treatment for opioid use disorder: acceptability, engagement and treatment retention2025
  4. 4Retention of people who inject drugs enrolled in a ‘medications for opioid use disorder’ (MOUD) programme in Uganda2024 · 10 citations
  5. 5Retention of patients in opioid substitution treatment: A systematic review2020 · 305 citations