This review demonstrates how cynarin and phytochemicals show anti-cancer effects in modern medicine, indicating their therapeutic potential.
Traditional medicine uses artichokes, which are perennial plants that contain compounds with a variety of therapeutic uses. Because of their strong hepatoprotective, anti-inflammatory, and antioxidant properties, the phytochemical makeup of artichokes and their main bioactive constituents cynarin, chlorogenic acid, and flavonoids were examined. Preclinical and clinical data supporting the pharmacological profile of artichokes, including its anti-diabetic, anti-microbial, neuroprotective, cardioprotective, and anti-cancer effects, are also covered. By lowering oxidative stress, suppressing inflammatory cytokine levels, and triggering apoptosis in tumor cells, its method of action offers mechanistic insights into how this drug alters molecular pathways. Despite their immense potential for usage, extracts have not been standardized, and their effectiveness varies. Toxicological investigations highlight the need to be mindful of infrequent but safe side effects and drug combinations. Additionally, this paper examines the use of artichokes in pharmaceutical formulations, nutraceuticals, and functional foods to address contemporary health issues such as cancer, neurodegenerative illnesses, and neurological syndrome. Lastly, the topic of how extraction methods, genetic studies, and nanoformulation tools could improve treatment results is discussed. By bridging the gap between conventional wisdom and its scientific foundation, this review demonstrates the incredible potential of artichokes to completely revolutionize healthcare procedures. It is advised that they be standardized and utilized as a natural medicinal agent for modern ailments in light of these findings.
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Sonali et al. (2025) studied this question.
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