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Combined retrospective and prospective analysis reveals histopathological profiles in cervical biopsies, highlighting alcohol's role in carcinoma prevalence.
Background:Cervical cancer is a type of cancer that develops in the cells of the uterine cervix. It is primarily caused by infection with the human papillomavirus (HPV), transmitted through unprotected sexual intercourse. As a major public health concern, this cancer motivated our study, which aimed to evaluate the histopathological profile of cervical biopsies received at the anatomic pathology laboratory of Laquintinie Hospital in Douala. Methods: This was a combined retrospective and prospective study conducted over a one-year period, from June 2023 to May 2024. The study sought to provide useful information for policymakers and the scientific community to improve cervical cancer prevention and treatment strategies. Conclusion:Additionally, alcohol consumption appeared to be an associated factor: the prevalence of carcinomas was 26.6% among women who consumed alcohol, compared to 7.1% for adenocarcinomas. As for precancerous lesions, mild dysplasia was more frequent among alcohol-consuming women (26.6%), compared to moderate (3.0%) and severe dysplasia (5.2%).
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Bertrand et al. (2025) studied this question.
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