Giant Pleomorphic Adenoma of the Maxillary Sinus with Orbital Extension: A Case Report

Pleomorphic adenoma (PA) is the most common benign neoplasm of salivary gland origin involving both major and minor glands. The most frequent site is the parotid gland. It is rare in the accessory salivary glands, preferably located in the oral mucosa. Incidence of its origin in the respiratory tract is extremely rare, and the occurrence is even lower in the maxillary sinus. We report a case of a 57 years old female presented with a swelling of the middle third of the face and an exophthalmos. Clinical evaluation and imaging studies revealed a huge mass centered on the maxillary sinus. A maxillectomy was performed and the the histopathology report was consistent with a PA. The orbital involvement due to extension as described in this case is very uncommon. These are benign salivary gland neoplasms that can grow into extensive sizes if left untreated and hence need to be diagnosed early.