Case report highlights stroke complications in an 11-year-old boy with sickle cell disease, suggesting cerebral stenosis as a key mechanism.
Stroke, is a significant cause of morbidity and mortality in sickle cell disease, occurring with an incidence of 10 to 25%. The risk of Stoke is highest during the first decade of life, Extensive research has established that cerebral stenosis, involving the circle of Willis, is the most common mechanism in children. A report of 11-year-old boy with Sickle Cell Anemia presented with history of left sided hemiplegia for 3 weeks that was of sudden onset. Computerized tomography of the brain revealed an increasing sulcal space more marked in frontal lobes associated with hypo attenuating area in the right frontal lobe. Features suggestive of Brain atrophy and right frontal lobe Ischemic.
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Kato et al. (2025) studied this question.
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