This method shows improved detection of pathogenic bacteria in single cells, suggesting a reliable approach using capillary-assisted particle assembly.
Key Points
This method enables rapid identification of pathogenic bacteria at the single-cell level, significantly improving diagnostic precision.
Maximum Raman intensities are achieved through a reflective Ag/SiO2 film, enhancing signals from single bacterial cells effectively.
Capillarity-assisted particle assembly aligns cells with the most active Raman region, simplifying the detection procedure.
The developed sensing platform can potentially transform clinical diagnostics, providing accurate results without extensive sample preparation.