Co- Existence of Persistent Hyperplastic Primary Vitreous in Right Eye and Morning Glory Syndrome in Left Eye– A Rare Clinical Case Report

Morning Glory Syndrome (MGS) is an uncommon congenital anomaly of the optic disc, characterized by a funnel-shaped excavation, a central tuft of glial tissue, and radially oriented retinal vessels. This condition frequently leads to significant visual deficits due to early developmental disruptions during embryogenesis. MGS is commonly associated with several ocular conditions such as retinal detachment, cataracts, and strabismus, as well as systemic disorders including basal encephalocele and Moyamoya disease [1,5,7]. A notable coexisting condition is Persistent Hyperplastic Primary Vitreous (PHPV), which shares similar developmental pathways and substantially influences the clinical presentation of MGS. This report presents a case demonstrating marked PHPV with lens colobomas in an MGS patient, emphasizing the complex developmental interrelation between these anomalies. Awareness of these associations is essential for prompt diagnosis, effective management of complications, and early detection of potentially life-threatening conditions [1–3].