This study examines sfrp gene expression in Eupentacta fraudatrix during regeneration, suggesting its role in water-vascular system formation.
Secreted Frizzled‐related proteins (SFRPs) are a small, ancient family of extracellular signaling pathway agonists and antagonists. In this study, we examined their expression patterns during regeneration in the holothurian Eupentacta fraudatrix using whole‐mount in situ hybridization. Our results suggest that both genes are involved in proper water‐vascular system formation and coelomic epithelium homeostasis in holothurians.
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Konstantin Sadriev (2025) studied this question.
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