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September 10, 2025CureusOpen Access

Baseline Hepatitis B Surface Antibody (Anti-HBs) Titers in Healthcare Workers at a Tertiary Care Center in Chennai, India

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Authors

VKVaishnavi KondaSVShanti Vijayaraghavan

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Overview

Cross-sectional study shows high vaccine response to hepatitis B in healthcare workers, indicating age-related variations.

Key Points

  • 93.0% of healthcare workers developed a protective response to the hepatitis B vaccine, highlighting effective immunization.
  • Vaccine response varied significantly by age, with the highest rate of 95.6% in the 26-35 age group, pointing to demographic factors.
  • The study involved 1,909 healthcare workers and utilized statistical analyses to explore associations between demographic variables and vaccine response.
  • The presence of a 7.0% non-responder group underscores the need for personalized immunization strategies to enhance overall effectiveness.

Cite This Study

Konda et al. (2025) studied this question.

synapsesocial.com/papers/68c1ae6654b1d3bfb60e609ehttps://doi.org/10.7759/cureus.88973
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Seroprotection Status of Hepatitis B Vaccination Among Healthcare Workers in a Tertiary Care Hospital: A Cross-Sectional Study2026
  2. 2Anti-HBS antibody status of healthcare workers in Pushpagiri Institute of Medical sciences and Research Centre2014
  3. 3Hepatitis B vaccine immunity in healthcare workers: Seroprotection and cellular immune signatures of waning response2026
  4. 4Measuring the Invisible Armor Due to Emerging Hepatitis B Virus Infection: Anti-hepatitis B surface Antibody Levels and Vaccination Coverage among Healthcare Workers in a Tertiary Care Hospital, Salem2026
  5. 5Evaluating the Status of Hepatitis B Vaccination in Healthcare Workers at a Central Laboratory in a Tertiary Care Hospital and Research Centre2024 · 2 citations