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Acute skin toxicity in breast cancer patients following different fractionation regimens of postoperative radiotherapy

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Patients receiving the standard fractionated regimen experienced significantly more acute skin toxicity than those receiving hypofractionated radiotherapy.
The standard regimen (50 Gy in 25 fractions) led to more severe skin reactions, particularly notable were grades I and II of erythema and desquamation.
Prospective analysis involved 44 breast cancer patients split into two groups based on different radiotherapy fractionation regimens.
Findings highlight the necessity for careful selection of radiotherapy approaches due to varying skin toxicity outcomes in breast cancer treatment.

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Prospective study shows higher acute skin toxicity in patients receiving standard fractionated radiotherapy, suggesting better options are needed.

Radić et al. (2025) studied this question.

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Prospective study shows higher acute skin toxicity in patients receiving standard fractionated radiotherapy, suggesting better options are needed.