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September 10, 2025Optics Letters

Optimized optical-acoustic combiner for high-sensitivity, high-speed three-dimensional photoacoustic microscopy

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Authors

KZKe ZhangNanjing Agricultural University ETEr-Qi TuShanghai Jiao Tong University XFXiao-Yong FangShanghai Jiao Tong University

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Implication

This study demonstrates enhanced acoustic detection sensitivity and extended depth of focus in vascular imaging, highlighting key advancements in photoacoustic microscopy.

Key Points

The optimized optical-acoustic combiner design achieved the highest sensitivity in photoacoustic microscopy.
Volumetric imaging quality significantly improved, demonstrating enhanced visibility and vessel density in biological tissues.
A novel curved scanning method extended the depth of focus from 1.74 mm to ~10 mm, facilitating better imaging.
Phantom and in vivo experiments validated the enhanced performance of the photoacoustic microscopy system.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68c1ae7f54b1d3bfb60e6c06 https://doi.org/10.1364/ol.572179

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Implication

This study demonstrates enhanced acoustic detection sensitivity and extended depth of focus in vascular imaging, highlighting key advancements in photoacoustic microscopy.

Optimized optical-acoustic combiner for high-sensitivity, high-speed three-dimensional photoacoustic microscopy

Discussion

Member takes

Implication

Key Points

Cite This Study

Optimized optical-acoustic combiner for high-sensitivity, high-speed three-dimensional photoacoustic microscopy

Discussion

Member takes

Implication

Key Points

Cite This Study

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