Biotechnology in post -traumatic regeneration of bone tissue

Bone regeneration is a complex, well-organized physiological process of bone formation that can be observed during normal fracture healing and that participates in continuous remodeling throughout life. Bone has the potential for regeneration, which can best be seen by its repair after a fracture. Bone is capable of healing fractures or local defects with new tissue and regeneration without loss of high structural organization and scarring. Despite the fact that with reparative osteogenesis there are prerequisites for the complete restoration of bone structures to replace the lost ones, the percentage of complications after traumatic injuries remains quite high. This necessitates the development of new experimental and theoretical approaches to the problem of bone regeneration, including elucidating the biological mechanisms underlying the process of chemotaxis and cell differentiation in the area of traumatic injury, studying the formation of complex cellular and tissue components of the regenerate, the conditions under which this occurs, and the factors governing osteoreparation.