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September 10, 2025MoleculesOpen Access

Effect of Mixing Technology on Homogeneity and Quality of Sodium Naproxen Tablets: Technological and Analytical Evaluation Using HPLC Method

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Authors

MPMateusz PrzywaraRLRegina Lech-PrzywaraPRPatrycja Rupar

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Overview

Evaluates mixing techniques for sodium naproxen tablets, suggesting optimal methods for content uniformity and quality assessment.

Key Points

  • The V-type mixer produced the most consistent tablet weight and thickness, highlighting its effectiveness despite flow issues.
  • Vibratory milling achieved superior API content uniformity, illustrating the importance of mixing techniques in dosage forms.
  • Characterization included assessing flowability and compressibility, crucial for ensuring proper tablet formulations.
  • The fast and robust HPLC method enabled reliable API quantification, simplifying analytical processes in pharmaceutical settings.

Cite This Study

Przywara et al. (2025) studied this question.

synapsesocial.com/papers/68c1afb954b1d3bfb60e6f69https://doi.org/10.3390/molecules30153119
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