Current concepts of hypercalcemia in sarcoidosis

Currently, the prevalence of sarcoidosis is rapidly increasing. And there are frequent cases of increased calcium, which in modern clinical realities are not given enough attention. The pathology of calcium metabolism in this disease has a multi-component nature and can not only worsen the patient's condition, but also determine the degree of disease activity. Our article discusses the main links in the pathogenesis of calcium metabolism disorders in sarcoidosis, as well as renal dysfunction that can occur as a result of this pathology. Attention is paid to changes in bone metabolism in patients with sarcoidosis as such (especially against the background of glucocorticoid therapy), and those formed as a result of long-term uncompensated hypercalcemia. An algorithm for examining a patient with hypercalcemia in sarcoidosis is also presented and ways to correct changes in calcium metabolism are outlined.