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Early Risk Stratification in a High-Mortality Study of Adult Trauma Patients: A Comparative Validation of RTS, SI, and ISS

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The injury severity score (ISS) had the highest discriminatory power for predicting mortality with an AUC of 0.88.
All three scoring systems—RTS, SI, and ISS—were significant predictors of in-hospital mortality in adult trauma patients.
The revised trauma score (RTS) demonstrated good discrimination with an AUC of 0.83, while shock index (SI) had an AUC of 0.76.
These findings suggest using physiological scores for initial assessment with ISS for definitive prognostication.

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Retrospective analysis evaluated revised trauma score and injury severity score in trauma patients, showing ISS has superior predictive performance.

Prasetyo et al. (2025) studied this question.

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Retrospective analysis evaluated revised trauma score and injury severity score in trauma patients, showing ISS has superior predictive performance.