Case report details cholestatic hepatitis in a young male with primary Epstein-Barr virus infection, suggesting further awareness needed.
Primary Epstein-Barr virus (EBV) infection is a herpes virus characterized by sore throat, fever, and lymphadenopathy. Liver involvement is characterized by moderate elevation of aminotransferases and hepatosplenomegaly, which regresses spontaneously. Cholestatic hepatitis in patients is a rare presentation of primary EBV infection. A 19-year-old male patient presented to the emergency department with complaints of nausea, vomiting, right upper quadrant pain, and mild sore throat for 2 days. Acute EBV infection was diagnosed based on serology results and no dilating lesions detected on radiological imaging. Healthcare professionals should keep in mind that EBV may also be involved in the etiology of cholestatic hepatitis.
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Erol et al. (2025) studied this question.
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