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September 10, 2025

Role of Cannabinoids in Chronic Pain Management: A Pharmacodynamic Perspective

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Cannabinoids show significant potential to manage chronic pain effectively and safely.
Evidence indicates cannabinoids block nociceptive transmission and offer anti-inflammatory benefits in pain management.
Methodological challenges include dosage variability and safety-related effects that hinder cannabinoid efficacy.
Future research should focus on standardized dosing in larger populations to optimize cannabinoid therapies.

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This review demonstrates cannabinoids' mixed effects on pain in adults, suggesting a potential role in management.

Banchhor et al. (2025) studied this question.

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