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Pregnancy Outcomes Following Assisted Reproductive Technology in Advanced Maternal Age Primiparous Women: A Retrospective Cohort Study

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Retrospective cohort study assesses maternal and neonatal outcomes in ART versus spontaneous conception, highlighting risks.

ART is linked to a higher risk of preeclampsia and cesarean delivery in advanced maternal age women, and indicates a need for careful management.
The study analyzed data from 2329 AMA primiparous women, comparing ART and spontaneous conception outcomes by maternal age and BMI.
Logistic regression revealed significant differences in neonatal outcomes between ART and spontaneous conception births, affecting NICU admissions.
Findings stress the importance of preconception counseling for women of advanced maternal age seeking assisted reproductive technology.

Deng et al. (2025) studied this question.

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