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September 10, 2025AndrologiaOpen Access

The Effects of miR‐425‐3p and Seminal Microbiota on Semen Parameters: Insights Into Male Infertility

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Authors

OBOsamah BatihaRARaghad Abu-DiakQAQutaiba Ababneh

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Overview

Observational analysis reveals links between miR-425-3p, seminal microbiota, and sperm motility in male infertility.

Key Points

  • Increased expression of miR-425-3p correlates with reduced sperm motility, highlighting its potential role in male infertility.
  • Semen samples from individuals with poor motility showed elevated MDA levels, indicating higher oxidative stress.
  • Microbial analysis revealed that higher bacterial loads were associated with better sperm motility, suggesting beneficial microbial effects.
  • Diverse microbial profiles were identified, with specific genera linked to variations in sperm motility and reproductive health.

Cite This Study

Batiha et al. (2025) studied this question.

synapsesocial.com/papers/68c1b36054b1d3bfb60ea4f0https://doi.org/10.1155/and/6262703
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