Synthesis of the nanozyme Pt/PDA and its application in the detection of bisphenol A

In recent years, people have paid increasing attention to food safety. Various types of food hazards are present in food, including pesticide residues, veterinary drug residues, toxins, heavy metals, etc. Food hazards pose a significant threat to human health, so there is an urgent need to develop rapid and accurate detection methods. In this paper, a Pt/PDA composite material with a hollow structure was designed and synthesized, and it was used as a nanozyme to establish a new colorimetric detection platform for bisphenol A (BPA). The results of the catalytic performance study show that the prepared Pt/PDA has both oxidase-like and peroxidase-like catalytic activities. Based on the phenomenon that the presence of BPA inhibits the oxidation of TMB, a new method for the colorimetric detection of BPA using Pt/PDA + TMB + H 2 O 2 was constructed. There is a linear relationship between the absorbance of Ox-TMB at 448 nm and the concentration of BPA. The linear range for the detection of BPA is between 1.5 and 850 μM, and the detection limit is 1.23 μM. This method has high selectivity when detecting BPA.