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September 10, 2025International Journal of Pharmaceutical Sciences and Nanotechnology

Formulation and Evaluation of Ticagrelor Nanosuspension Loaded Fast Dissolving Sublingual Films

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Authors

RKRoshan R. KambleSMShrikant S. MagdumRSRohit Shah

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Overview

This research develops nanosuspension-loaded sublingual films, improving bioavailability in patients, suggesting a novel delivery method.

Key Points

  • The optimized ticagrelor nanosuspension showed a significant improvement in solubility and bioavailability.
  • Key evaluation metrics demonstrated a particle size of 190 nm and high encapsulation efficiency of 92.44%.
  • Sublingual films displayed rapid disintegration time of 63.31 seconds and an impressive in vitro drug release of 92.60%.
  • This formulation approach could potentially enhance the delivery of other poorly soluble medications.

Cite This Study

Kamble et al. (2025) studied this question.

synapsesocial.com/papers/68c1b61454b1d3bfb60eb577https://doi.org/10.37285/ijpsn.2025.18.3.6
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