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September 10, 2025Advances in UrologyOpen Access

Effect of Intraoperative Local Administration of Tranexamic Acid on Hemorrhage in Patients Undergoing Open Prostatectomy: A Double‐Blinded Randomized Parallel‐Group Trial

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Double-blinded trial demonstrates reduced hemorrhage and transfusion rates in BPH surgery.

Intraoperative local administration of tranexamic acid significantly reduced perioperative blood loss.
Perioperative blood loss was 116.65 mL in the TXA group versus 210.27 mL in the control group, p = 0.001.
This randomized controlled trial involved 140 patients undergoing surgery for benign prostatic hyperplasia.
TXA use suggests a safe option for minimizing surgical bleeding, pending further validation.

Hemmati-Ghavshough et al. (2025) studied this question.

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