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Synthesis reveals a fluorescent probe activates fluorescence in response to sulfinic acids, suggesting potential for protein labeling.
A fluorescent naphthalimide azocarboxylate was successfully tethered to a polymethacrylate backbone. The resulting polymeric material exhibits efficient turn-on fluorescence upon sulfinate addition onto the azo moiety forming covalent bonding, with minimal quenching effects from non-emissive isomeric units, demonstrating its potential for developing fluorescent labelling for sulfinated-proteins.
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Tanimoto et al. (2025) studied this question.
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