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September 10, 2025JCO Global OncologyOpen Access

Point-of-Care Urine Metabolomics Test to Diagnose Colorectal Cancers in Low- and Middle-Income Countries: A Pilot Controlled Trial in Southwestern Nigeria

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Authors

AAAdeleye Abiodun AdeomiOAOlusegun Isaac AlatiseDWDavid S. Wishart

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Overview

Pilot trial evaluates a point-of-care urine metabolomics test for colorectal cancer, showing high sensitivity and patient acceptance rates.

Key Points

  • The urine metabolomics test achieved a sensitivity of 94.5% and specificity of 81.58% for colorectal cancer.
  • With a high acceptance rate of 98.6%, the test indicates strong patient willingness to pay approximately $5.2 for screening.
  • A pilot-controlled trial involved 72 patients, comparing cases with colorectal cancer and at-risk controls in Nigeria.
  • The test showed potential to improve diagnostic processes and reduce referrals to colonoscopy in low-resource settings.

Cite This Study

Adeomi et al. (2025) studied this question.

synapsesocial.com/papers/68c1b81f54b1d3bfb60ec51chttps://doi.org/10.1200/go-25-00062
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